Rapid Rise in Mucormycosis - Possible Causes and Review

Mucormycosis is a life-threatening fungal infection in immune compromised patients with diabetes, post-transplant, retroviral disease, and those who are on long-term immunosuppression for various chronic diseases. The fungi interact with the endothelial cells which cause vascular invasion leading to infarction and necrosis of the host tissue. The most common presentation of mucor is rhino-orbitocerebral. The incidence of this fulminant disease has been increasing rapidly for the past couple of years in India, especially in patients post- COVID infection within several weeks after recovering from COVID. The rapid rise in cases especially in patients with COVID and those recovering from COVID raises many questions among the physicians and some of them are discussed in this article.